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Transcriptomic changes in mouse embryonic stem cells exposed to thalidomide during spontaneous differentiation

Thalidomide is a potent developmental toxicant that induces a range of birth defects, notably severe limb malformations. To unravel the molecular mechanisms underpinning the teratogenic effects of thalidomide, we used microarrays to study transcriptomic changes induced by thalidomide in an in vitro...

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Detalles Bibliográficos
Autores principales: Gao, Xiugong, Sprando, Robert L., Yourick, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510476/
https://www.ncbi.nlm.nih.gov/pubmed/26217789
http://dx.doi.org/10.1016/j.dib.2015.05.014