Cargando…
Transcriptomic changes in mouse embryonic stem cells exposed to thalidomide during spontaneous differentiation
Thalidomide is a potent developmental toxicant that induces a range of birth defects, notably severe limb malformations. To unravel the molecular mechanisms underpinning the teratogenic effects of thalidomide, we used microarrays to study transcriptomic changes induced by thalidomide in an in vitro...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510476/ https://www.ncbi.nlm.nih.gov/pubmed/26217789 http://dx.doi.org/10.1016/j.dib.2015.05.014 |