Bryostatin activates HIV-1 latent expression in human astrocytes through a PKC and NF-ĸB-dependent mechanism

Multiple studies have shown that HIV-1 patients may develop virus reservoirs that impede eradication; these reservoirs include the central nervous system (CNS). Despite an undetectable viral load in patients treated with potent antiretrovirals, current therapy is unable to purge the virus from these...

Descripción completa

Detalles Bibliográficos
Autores principales: Díaz, Laura, Martínez-Bonet, Marta, Sánchez, Javier, Fernández-Pineda, Alejandra, Jiménez, José Luis, Muñoz, Eduardo, Moreno, Santiago, Álvarez, Susana, Muñoz-Fernández, Mª Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510492/
https://www.ncbi.nlm.nih.gov/pubmed/26199173
http://dx.doi.org/10.1038/srep12442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510492/
https://www.ncbi.nlm.nih.gov/pubmed/26199173
http://dx.doi.org/10.1038/srep12442

Ejemplares similares