K-bZIP Mediated SUMO-2/3 Specific Modification on the KSHV Genome Negatively Regulates Lytic Gene Expression and Viral Reactivation

SUMOylation is associated with epigenetic regulation of chromatin structure and transcription. Epigenetic modifications of herpesviral genomes accompany the transcriptional switch of latent and lytic genes during the virus life cycle. Here, we report a genome-wide comparison of SUMO paralog modifica...

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Detalles Bibliográficos
Autores principales: Yang, Wan-Shan, Hsu, Hung-Wei, Campbell, Mel, Cheng, Chia-Yang, Chang, Pei-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510548/
https://www.ncbi.nlm.nih.gov/pubmed/26197391
http://dx.doi.org/10.1371/journal.ppat.1005051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510548/
https://www.ncbi.nlm.nih.gov/pubmed/26197391
http://dx.doi.org/10.1371/journal.ppat.1005051

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