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K-bZIP Mediated SUMO-2/3 Specific Modification on the KSHV Genome Negatively Regulates Lytic Gene Expression and Viral Reactivation
SUMOylation is associated with epigenetic regulation of chromatin structure and transcription. Epigenetic modifications of herpesviral genomes accompany the transcriptional switch of latent and lytic genes during the virus life cycle. Here, we report a genome-wide comparison of SUMO paralog modifica...
Autores principales: | Yang, Wan-Shan, Hsu, Hung-Wei, Campbell, Mel, Cheng, Chia-Yang, Chang, Pei-Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510548/ https://www.ncbi.nlm.nih.gov/pubmed/26197391 http://dx.doi.org/10.1371/journal.ppat.1005051 |
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