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Cleavable ester linked magnetic nanoparticles for labeling of solvent exposed primary amine groups of peptides/proteins

Covalent labeling of solvent exposed amino acid residues using chemical reagents/crosslinkers followed by mass spectrometric analysis can be used to determine the solvent accessible amino acids of a protein. A variety of chemical reagents containing cleavable bonds were developed to label abundantly...

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Detalles Bibliográficos
Autores principales: Patil, Ujwal S., Osorno, Laura, Ellender, Angela, Grimm, Casey, Tarr, Matthew A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510550/
https://www.ncbi.nlm.nih.gov/pubmed/26217806
http://dx.doi.org/10.1016/j.dib.2015.05.025