Immortalisation with hTERT Impacts on Sulphated Glycosaminoglycan Secretion and Immunophenotype in a Variable and Cell Specific Manner

BACKGROUND: Limited options for the treatment of cartilage damage have driven the development of tissue engineered or cell therapy alternatives reliant on ex vivo cell expansion. The study of chondrogenesis in primary cells is difficult due to progressive cellular aging and senescence. Immortalisati...

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Detalles Bibliográficos
Autores principales: Dale, Tina P., de Castro, Alice, Kuiper, Nicola J., Parkinson, E. Kenneth, Forsyth, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510558/
https://www.ncbi.nlm.nih.gov/pubmed/26196672
http://dx.doi.org/10.1371/journal.pone.0133745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510558/
https://www.ncbi.nlm.nih.gov/pubmed/26196672
http://dx.doi.org/10.1371/journal.pone.0133745

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