Diversity and Impact of Rare Variants in Genes Encoding the Platelet G Protein-Coupled Receptors

Platelet responses to activating agonists are influenced by common population variants within or near G protein-coupled receptor (GPCR) genes that affect receptor activity. However, the impact of rare GPCR gene variants is unknown. We describe the rare single nucleotide variants (SNVs) in the coding...

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Detalles Bibliográficos
Autores principales: Jones, Matthew L., Norman, Jane E., Morgan, Neil V., Mundell, Stuart J., Lordkipanidzé, Marie, Lowe, Gillian C., Daly, Martina E., Simpson, Michael A., Drake, Sian, Watson, Steve P., Mumford, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Schattauer 2015
Materias:
Cellular Haemostasis and Platelets
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510585/
https://www.ncbi.nlm.nih.gov/pubmed/25567036
http://dx.doi.org/10.1160/TH14-08-0679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510585/
https://www.ncbi.nlm.nih.gov/pubmed/25567036
http://dx.doi.org/10.1160/TH14-08-0679

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