A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo

Notochord-derived Sonic Hedgehog (Shh) is essential for dorsoventral patterning of the overlying neural tube. Increasing concentration and duration of Shh signal induces progenitors to acquire progressively more ventral fates. We show that Notch signalling augments the response of neuroepithelial ce...

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Detalles Bibliográficos
Autores principales: Stasiulewicz, Magdalena, Gray, Shona D., Mastromina, Ioanna, Silva, Joana C., Björklund, Mia, Seymour, Philip A., Booth, David, Thompson, Calum, Green, Richard J., Hall, Emma A., Serup, Palle, Dale, J. Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510595/
https://www.ncbi.nlm.nih.gov/pubmed/25995356
http://dx.doi.org/10.1242/dev.125237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510595/
https://www.ncbi.nlm.nih.gov/pubmed/25995356
http://dx.doi.org/10.1242/dev.125237

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