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Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes

Gradients of the fast transient outward K(+) current (I(to,f)) contribute to heterogeneity of ventricular repolarization in a number of species. Cardiac I(to,f) levels and gradients change notably with heart disease. Human cardiac I(to,f) appears to be encoded by the Kv4.3 pore-forming α-subunit plu...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Kim, Kyoung-Han, Morales, Michael J., Heximer, Scott P., Hui, Chi-chung, Backx, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510596/
https://www.ncbi.nlm.nih.gov/pubmed/26196737
http://dx.doi.org/10.1371/journal.pone.0133274