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Modeling Photo-Bleaching Kinetics to Create High Resolution Maps of Rod Rhodopsin in the Human Retina

We introduce and describe a novel non-invasive in-vivo method for mapping local rod rhodopsin distribution in the human retina over a 30-degree field. Our approach is based on analyzing the brightening of detected lipofuscin autofluorescence within small pixel clusters in registered imaging sequence...

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Detalles Bibliográficos
Autores principales: Ehler, Martin, Dobrosotskaya, Julia, Cunningham, Denise, Wong, Wai T., Chew, Emily Y., Czaja, Wojtek, Bonner, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510609/
https://www.ncbi.nlm.nih.gov/pubmed/26196397
http://dx.doi.org/10.1371/journal.pone.0131881