Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice

Roles of soluble epoxide hydrolase (sEH), the enzyme responsible for hydrolysis of epoxyeicosatrienoic acids (EETs) to their diols (DHETs), in the coronary circulation and cardiac function remain unknown. We tested the hypothesis that compromising EET hydrolysis/degradation, via sEH deficiency, lowe...

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Detalles Bibliográficos
Autores principales: Qin, Jun, Sun, Dong, Jiang, Houli, Kandhi, Sharath, Froogh, Ghezal, Hwang, Sung Hee, Hammock, Bruce D, Wolin, Michael S, Thompson, Carl I, Hintze, Thomas H, Huang, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510629/
https://www.ncbi.nlm.nih.gov/pubmed/26071213
http://dx.doi.org/10.14814/phy2.12427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510629/
https://www.ncbi.nlm.nih.gov/pubmed/26071213
http://dx.doi.org/10.14814/phy2.12427

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