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TD-60 links RalA GTPase function to the CPC in mitosis

TD-60 (also known as RCC2) is a highly conserved protein that structurally resembles the Ran guanine exchange factor (GEF) RCC1, but has not previously been shown to have GEF activity. TD-60 has a typical chromosomal passenger complex (CPC) distribution in mitotic cells, but associates with integrin...

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Detalles Bibliográficos
Autores principales: Papini, Diana, Langemeyer, Lars, Abad, Maria A., Kerr, Alastair, Samejima, Itaru, Eyers, Patrick A., Jeyaprakash, A. Arockia, Higgins, Jonathan M. G., Barr, Francis A., Earnshaw, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510650/
https://www.ncbi.nlm.nih.gov/pubmed/26158537
http://dx.doi.org/10.1038/ncomms8678