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A highly selective biosynthetic pathway to non-natural C(50) carotenoids assembled from moderately selective enzymes
Synthetic biology aspires to construct natural and non-natural pathways to useful compounds. However, pathways that rely on multiple promiscuous enzymes may branch, which might preclude selective production of the target compound. Here, we describe the assembly of a six-enzyme pathway in Escherichia...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510654/ https://www.ncbi.nlm.nih.gov/pubmed/26168783 http://dx.doi.org/10.1038/ncomms8534 |