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A highly selective biosynthetic pathway to non-natural C(50) carotenoids assembled from moderately selective enzymes

Synthetic biology aspires to construct natural and non-natural pathways to useful compounds. However, pathways that rely on multiple promiscuous enzymes may branch, which might preclude selective production of the target compound. Here, we describe the assembly of a six-enzyme pathway in Escherichia...

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Detalles Bibliográficos
Autores principales: Furubayashi, Maiko, Ikezumi, Mayu, Takaichi, Shinichi, Maoka, Takashi, Hemmi, Hisashi, Ogawa, Takuya, Saito, Kyoichi, Tobias, Alexander V, Umeno, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510654/
https://www.ncbi.nlm.nih.gov/pubmed/26168783
http://dx.doi.org/10.1038/ncomms8534