KRAS-dependent sorting of miRNA to exosomes

Mutant KRAS colorectal cancer (CRC) cells release protein-laden exosomes that can alter the tumor microenvironment. To test whether exosomal RNAs also contribute to changes in gene expression in recipient cells, and whether mutant KRAS might regulate the composition of secreted microRNAs (miRNAs), w...

Descripción completa

Detalles Bibliográficos
Autores principales: Cha, Diana J, Franklin, Jeffrey L, Dou, Yongchao, Liu, Qi, Higginbotham, James N, Demory Beckler, Michelle, Weaver, Alissa M, Vickers, Kasey, Prasad, Nirpesh, Levy, Shawn, Zhang, Bing, Coffey, Robert J, Patton, James G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510696/
https://www.ncbi.nlm.nih.gov/pubmed/26132860
http://dx.doi.org/10.7554/eLife.07197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510696/
https://www.ncbi.nlm.nih.gov/pubmed/26132860
http://dx.doi.org/10.7554/eLife.07197

Ejemplares similares