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Docosahexaenoic (DHA) modulates phospholipid-hydroperoxide glutathione peroxidase (Gpx4) gene expression to ensure self-protection from oxidative damage in hippocampal cells

Docosahexaenoic acid (DHA, 22:6n-3) is a unique polyunsaturated fatty acid particularly abundant in nerve cell membrane phospholipids. DHA is a pleiotropic molecule that, not only modulates the physicochemical properties and architecture of neuronal plasma membrane, but it is also involved in multip...

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Detalles Bibliográficos
Autores principales: Casañas-Sánchez, Verónica, Pérez, José A., Fabelo, Noemí, Quinto-Alemany, David, Díaz, Mario L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510835/
https://www.ncbi.nlm.nih.gov/pubmed/26257655
http://dx.doi.org/10.3389/fphys.2015.00203