Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure

The cytoskeleton is widely considered essential for neurulation, yet the mouse spinal neural tube can close despite genetic and non-genetic disruption of the cytoskeleton. To investigate this apparent contradiction, we applied cytoskeletal inhibitors to mouse embryos in culture. Preventing actomyosi...

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Detalles Bibliográficos
Autores principales: Escuin, Sarah, Vernay, Bertrand, Savery, Dawn, Gurniak, Christine B., Witke, Walter, Greene, Nicholas D. E., Copp, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510849/
https://www.ncbi.nlm.nih.gov/pubmed/26040287
http://dx.doi.org/10.1242/jcs.164574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510849/
https://www.ncbi.nlm.nih.gov/pubmed/26040287
http://dx.doi.org/10.1242/jcs.164574

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