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Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure
The cytoskeleton is widely considered essential for neurulation, yet the mouse spinal neural tube can close despite genetic and non-genetic disruption of the cytoskeleton. To investigate this apparent contradiction, we applied cytoskeletal inhibitors to mouse embryos in culture. Preventing actomyosi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510849/ https://www.ncbi.nlm.nih.gov/pubmed/26040287 http://dx.doi.org/10.1242/jcs.164574 |