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Alternative routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4

Insulin-stimulated delivery of glucose transporters (GLUT4, also known as SLC2A4) from specialized intracellular GLUT4 storage vesicles (GSVs) to the surface of fat and muscle cells is central to whole-body glucose regulation. This translocation and subsequent internalization of GLUT4 back into intr...

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Detalles Bibliográficos
Autores principales: Kioumourtzoglou, Dimitrios, Pryor, Paul R., Gould, Gwyn W., Bryant, Nia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510850/
https://www.ncbi.nlm.nih.gov/pubmed/26071524
http://dx.doi.org/10.1242/jcs.166561