TORC2 mediates the heat stress response in Drosophila by promoting the formation of stress granules

The kinase TOR is found in two complexes, TORC1, which is involved in growth control, and TORC2, whose roles are less well defined. Here, we asked whether TORC2 has a role in sustaining cellular stress. We show that TORC2 inhibition in Drosophila melanogaster leads to a reduced tolerance to heat str...

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Detalles Bibliográficos
Autores principales: Jevtov, Irena, Zacharogianni, Margarita, van Oorschot, Marinke M., van Zadelhoff, Guus, Aguilera-Gomez, Angelica, Vuillez, Igor, Braakman, Ineke, Hafen, Ernst, Stocker, Hugo, Rabouille, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510851/
https://www.ncbi.nlm.nih.gov/pubmed/26054799
http://dx.doi.org/10.1242/jcs.168724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510851/
https://www.ncbi.nlm.nih.gov/pubmed/26054799
http://dx.doi.org/10.1242/jcs.168724

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