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Regions of ryanodine receptors that influence activation by the dihydropyridine receptor β(1a) subunit

BACKGROUND: Although excitation-contraction (EC) coupling in skeletal muscle relies on physical activation of the skeletal ryanodine receptor (RyR1) Ca(2+) release channel by dihydropyridine receptors (DHPRs), the activation pathway between the DHPR and RyR1 remains unknown. However, the pathway inc...

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Detalles Bibliográficos
Autores principales: Rebbeck, Robyn T., Willemse, Hermia, Groom, Linda, Casarotto, Marco G., Board, Philip G., Beard, Nicole A., Dirksen, Robert T., Dulhunty, Angela F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510890/
https://www.ncbi.nlm.nih.gov/pubmed/26203350
http://dx.doi.org/10.1186/s13395-015-0049-3