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Endothelial Connexin37 and Connexin40 participate in basal but not agonist-induced NO release

BACKGROUND: Connexin37 (Cx37) and Cx40 are crucial for endothelial cell-cell communication and homeostasis. Both connexins interact with endothelial nitric oxide synthase (eNOS). The exact contribution of these interactions to the regulation of vascular tone is unknown. RESULTS: Cx37 and Cx40 were e...

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Detalles Bibliográficos
Autores principales: Meens, Merlijn J, Alonso, Florian, Le Gal, Loïc, Kwak, Brenda R, Haefliger, Jacques-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510910/
https://www.ncbi.nlm.nih.gov/pubmed/26198171
http://dx.doi.org/10.1186/s12964-015-0110-1