DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer

Expression of oestrogen receptor (ESR1) determines whether a breast cancer patient receives endocrine therapy, but does not guarantee patient response. The molecular factors that define endocrine response in ESR1-positive breast cancer patients remain poorly understood. Here we characterize the DNA...

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Detalles Bibliográficos
Autores principales: Stone, Andrew, Zotenko, Elena, Locke, Warwick J., Korbie, Darren, Millar, Ewan K. A., Pidsley, Ruth, Stirzaker, Clare, Graham, Peter, Trau, Matt, Musgrove, Elizabeth A., Nicholson, Robert I., Gee, Julia M. W., Clark, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510968/
https://www.ncbi.nlm.nih.gov/pubmed/26169690
http://dx.doi.org/10.1038/ncomms8758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510968/
https://www.ncbi.nlm.nih.gov/pubmed/26169690
http://dx.doi.org/10.1038/ncomms8758

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