A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration

Although cell migration plays a central role in development and disease, the underlying molecular mechanism is not fully understood. Here we report that a phosphorylation-mediated molecular switch comprising deleted in liver cancer 1 (DLC1), tensin-3 (TNS3), phosphatase and tensin homologue (PTEN) a...

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Detalles Bibliográficos
Autores principales: Cao, Xuan, Kaneko, Tomonori, Li, Jenny S., Liu, An-Dong, Voss, Courtney, Li, Shawn S. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510974/
https://www.ncbi.nlm.nih.gov/pubmed/26166433
http://dx.doi.org/10.1038/ncomms8721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510974/
https://www.ncbi.nlm.nih.gov/pubmed/26166433
http://dx.doi.org/10.1038/ncomms8721

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