Generation of a stable packaging cell line producing high-titer PPT-deleted integration-deficient lentiviral vectors

The risk of insertional mutagenesis inherent to all integrating exogenous expression cassettes was the impetus for the development of various integration-defective lentiviral vector (IDLV) systems. These systems were successfully employed in a plethora of preclinical applications, underscoring their...

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Detalles Bibliográficos
Autores principales: Hu, Peirong, Li, Yedda, Sands, Mark S, McCown, Thomas, Kafri, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510976/
https://www.ncbi.nlm.nih.gov/pubmed/26229972
http://dx.doi.org/10.1038/mtm.2015.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510976/
https://www.ncbi.nlm.nih.gov/pubmed/26229972
http://dx.doi.org/10.1038/mtm.2015.25

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