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Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-seq data
BACKGROUND: Understanding the regulation of gene expression, including transcription start site usage, alternative splicing, and polyadenylation, requires accurate quantification of expression levels down to the level of individual transcript isoforms. To comparatively evaluate the accuracy of the m...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511015/ https://www.ncbi.nlm.nih.gov/pubmed/26201343 http://dx.doi.org/10.1186/s13059-015-0702-5 |