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Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-seq data

BACKGROUND: Understanding the regulation of gene expression, including transcription start site usage, alternative splicing, and polyadenylation, requires accurate quantification of expression levels down to the level of individual transcript isoforms. To comparatively evaluate the accuracy of the m...

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Detalles Bibliográficos
Autores principales: Kanitz, Alexander, Gypas, Foivos, Gruber, Andreas J., Gruber, Andreas R., Martin, Georges, Zavolan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511015/
https://www.ncbi.nlm.nih.gov/pubmed/26201343
http://dx.doi.org/10.1186/s13059-015-0702-5