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5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes

Glucocorticoids and androgens have both been implicated in the pathogenesis of nonalcoholic fatty liver disease (NAFLD); androgen deficiency in males, androgen excess in females, and glucocorticoid excess in both sexes are associated with NAFLD. Glucocorticoid and androgen action are regulated at a...

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Detalles Bibliográficos
Autores principales: Nasiri, Maryam, Nikolaou, Nikolaos, Parajes, Silvia, Krone, Nils P., Valsamakis, George, Mastorakos, George, Hughes, Beverly, Taylor, Angela, Bujalska, Iwona J., Gathercole, Laura L., Tomlinson, Jeremy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511138/
https://www.ncbi.nlm.nih.gov/pubmed/25974403
http://dx.doi.org/10.1210/en.2015-1149