Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort

Choline is an essential nutrient, and the amount needed in the diet is modulated by several factors. Given geographical differences in dietary choline intake and disparate frequencies of single-nucleotide polymorphisms (SNPs) in choline metabolism genes between ethnic groups, we tested the hypothesi...

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Detalles Bibliográficos
Autores principales: Silver, Matt J., Corbin, Karen D., Hellenthal, Garrett, da Costa, Kerry-Ann, Dominguez-Salas, Paula, Moore, Sophie E., Owen, Jennifer, Prentice, Andrew M., Hennig, Branwen J., Zeisel, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2015
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511208/
https://www.ncbi.nlm.nih.gov/pubmed/25921832
http://dx.doi.org/10.1096/fj.15-271056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511208/
https://www.ncbi.nlm.nih.gov/pubmed/25921832
http://dx.doi.org/10.1096/fj.15-271056

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