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The role of interleukin-1 beta in the pathophysiology of Schnitzler’s syndrome

INTRODUCTION: Schnitzler’s syndrome (SchS) is a disabling autoinflammatory disorder, characterized by a chronic urticarial rash, an M-protein, arthralgia, and other signs of systemic inflammation. Anti-interleukin-1 (IL-1) beta antibodies are highly effective, but the pathophysiology is still largel...

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Detalles Bibliográficos
Autores principales: de Koning, Heleen D., Schalkwijk, Joost, Stoffels, Monique, Jongekrijg, Johanna, Jacobs, Joannes F. M., Verwiel, Eugène, Koenen, Hans J. P. M., Preijers, Frank, Holzinger, Dirk, Joosten, Irma, van der Meer, Jos W. M., Simon, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511239/
https://www.ncbi.nlm.nih.gov/pubmed/26198339
http://dx.doi.org/10.1186/s13075-015-0696-0