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Novel link between prostaglandin E(2) (PGE(2)) and cholinergic signaling in lung cancer: The role of c-Jun in PGE(2)-induced α7 nicotinic acetylcholine receptor expression and tumor cell proliferation
BACKGROUND: Cyclooxygenase-2-derived prostaglandin E(2) (PGE(2)) stimulates tumor cell growth and progression. α7 nicotinic acetylcholine receptor (nAChR) is a major mediator of cholinergic signaling in tumor cells. In the present study, we investigated the mechanisms by which PGE(2) increases non-s...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511329/ https://www.ncbi.nlm.nih.gov/pubmed/26273406 http://dx.doi.org/10.1111/1759-7714.12219 |