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Verbascoside down-regulates some pro-inflammatory signal transduction pathways by increasing the activity of tyrosine phosphatase SHP-1 in the U937 cell line

Polyphenols are the major components of many traditional herbal remedies, which exhibit several beneficial effects including anti-inflammation and antioxidant properties. Src homology region 2 domain-containing phosphatase-1 (SHP-1) is a redox sensitive protein tyrosine phosphatase that negatively i...

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Detalles Bibliográficos
Autores principales: Pesce, Mirko, Franceschelli, Sara, Ferrone, Alessio, De Lutiis, Maria Anna, Patruno, Antonia, Grilli, Alfredo, Felaco, Mario, Speranza, Lorenza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511353/
https://www.ncbi.nlm.nih.gov/pubmed/25807993
http://dx.doi.org/10.1111/jcmm.12524