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FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation

Fibroblast growth factor 21 (FGF21) plays an important role in energy homoeostasis. The unaddressed question of FGF21’s effect on the development and progression of diabetic cardiomyopathy (DCM) is investigated here with FGF21 knockout (FGF21KO) diabetic mice. Type 1 diabetes was induced in both FGF...

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Detalles Bibliográficos
Autores principales: Yan, Xiaoqing, Chen, Jun, Zhang, Chi, Zhou, Shanshan, Zhang, Zhiguo, Chen, Jing, Feng, Wenke, Li, Xiaokun, Tan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511354/
https://www.ncbi.nlm.nih.gov/pubmed/25823710
http://dx.doi.org/10.1111/jcmm.12530