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Lipocalin-2 released in response to cerebral ischaemia mediates reperfusion injury in mice

Thrombolysis remains the only effective therapy to reverse acute ischaemic stroke. However, delayed treatment may cause serious complications including hemorrhagic transformation and reperfusion injury. The level of lipocalin-2 (LCN2) is elevated in the plasma of ischaemic stroke patients, but its r...

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Detalles Bibliográficos
Autores principales: Wang, Guona, Weng, Yi-Chinn, Han, Xiqian, Whaley, James D, McCrae, Keith R, Chou, Wen-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511361/
https://www.ncbi.nlm.nih.gov/pubmed/25702801
http://dx.doi.org/10.1111/jcmm.12538