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The effect of the sphingosine‐1‐phosphate analogue FTY720 on atrioventricular nodal tissue

The sphingosine‐1‐phosphate (S1P) receptor modulator, fingolimod (FTY720), has been used for the treatment of patients with relapsing forms of multiple sclerosis, but atrioventricular (AV) conduction block have been reported in some patients after the first dose. The underlying mechanism of this AV...

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Detalles Bibliográficos
Autores principales: Egom, Emmanuel E., Kruzliak, Peter, Rotrekl, Vladimir, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511369/
https://www.ncbi.nlm.nih.gov/pubmed/25864579
http://dx.doi.org/10.1111/jcmm.12549