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Review of the development of DNA methylation as a marker of response to neoadjuvant therapy and outcomes in rectal cancer
There is much debate around the preoperative treatment of colorectal cancer and, in particular, neoadjuvant chemoradiotherapy in locally advanced rectal cancer. This treatment carries a significant risk of harmful side effects and has a highly variable response rate. Predictive biomarkers have been...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511540/ https://www.ncbi.nlm.nih.gov/pubmed/26203306 http://dx.doi.org/10.1186/s13148-015-0111-3 |