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Review of the development of DNA methylation as a marker of response to neoadjuvant therapy and outcomes in rectal cancer

There is much debate around the preoperative treatment of colorectal cancer and, in particular, neoadjuvant chemoradiotherapy in locally advanced rectal cancer. This treatment carries a significant risk of harmful side effects and has a highly variable response rate. Predictive biomarkers have been...

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Detalles Bibliográficos
Autores principales:	Williamson, Jeremy S., Harris, Dean A., Beynon, John, Jenkins, Gareth J.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511540/ https://www.ncbi.nlm.nih.gov/pubmed/26203306 http://dx.doi.org/10.1186/s13148-015-0111-3

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