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Reactive Oxygen Species and Nuclear Factor Erythroid 2-Related Factor 2 Activation in Diabetic Nephropathy: A Hidden Target

Hyperglycemia, oxidative stress and renin-angiotensin system (RAS) dysfunction have been implicated in diabetic nephropathy (DN) progression, but the underlying molecular mechanisms are far from being fully understood. In addition to the systemic RAS, the existence of a local intrarenal RAS in renal...

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Detalles Bibliográficos
Autores principales: Abdo, Shaaban, Zhang, Shao-Ling, Chan, John S.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511631/
https://www.ncbi.nlm.nih.gov/pubmed/26213634
http://dx.doi.org/10.4172/2155-6156.1000547