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S-nitrosoglutathione-mediated STAT3 regulation in efficacy of radiotherapy and cisplatin therapy in head and neck squamous cell carcinoma()

S-nitrosoglutathione (GSNO) is an endogenous nitric oxide (NO) carrier that plays a critical role in redox based NO signaling. Recent studies have reported that GSNO regulates the activities of STAT3 and NF-κB via S-nitrosylation dependent mechanisms. Since STAT3 and NF-κB are key transcription fact...

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Detalles Bibliográficos
Autores principales: Kaliyaperumal, Kolanjiappan, Sharma, Anand K., McDonald, Daniel G., Dhindsa, Jasdeep S., Yount, Caroline, Singh, Avtar K., Won, Je-Seong, Singh, Inderjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511642/
https://www.ncbi.nlm.nih.gov/pubmed/26177470
http://dx.doi.org/10.1016/j.redox.2015.07.001