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A Multihit Model: Colitis Lessons from the Interleukin-10–deficient Mouse

Complex mechanisms are pulling the strings to initiate the development of inflammatory bowel disease. Current evidence indicates that an interaction of genetic susceptibilities (polymorphisms), environmental factors, and the host microbiota leads to a dysregulation of the mucosal immune system. In t...

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Detalles Bibliográficos
Autores principales: Keubler, Lydia M., Buettner, Manuela, Häger, Christine, Bleich, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511684/
https://www.ncbi.nlm.nih.gov/pubmed/26164667
http://dx.doi.org/10.1097/MIB.0000000000000468