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A Multihit Model: Colitis Lessons from the Interleukin-10–deficient Mouse
Complex mechanisms are pulling the strings to initiate the development of inflammatory bowel disease. Current evidence indicates that an interaction of genetic susceptibilities (polymorphisms), environmental factors, and the host microbiota leads to a dysregulation of the mucosal immune system. In t...
Autores principales: | Keubler, Lydia M., Buettner, Manuela, Häger, Christine, Bleich, André |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511684/ https://www.ncbi.nlm.nih.gov/pubmed/26164667 http://dx.doi.org/10.1097/MIB.0000000000000468 |
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