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The DNA-Binding Domain of S. pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers

During S-phase replication forks can stall at specific genetic loci. At some loci, the stalling events depend on the replisome components Schizosaccharomyces pombe Swi1 (Saccharomyces cerevisiae Tof1) and Swi3 (S. cerevisiae Csm3) as well as factors that bind DNA in a site-specific manner. Using a n...

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Detalles Bibliográficos
Autores principales: Zech, Juergen, Godfrey, Emma Louise, Masai, Hisao, Hartsuiker, Edgar, Dalgaard, Jacob Zeuthen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511789/
https://www.ncbi.nlm.nih.gov/pubmed/26201080
http://dx.doi.org/10.1371/journal.pone.0132595