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Cortical iron regulation and inflammatory response in Alzheimer's disease and APP(SWE)/PS1(ΔE9) mice: a histological perspective
Disruption of iron homeostasis and increased glial response are known to occur in brains afflicted by Alzheimer's disease (AD). While the APP/PS1 transgenic mouse model recapitulates the hallmark amyloid-beta plaque pathology of AD, it does so in a different neuronal mileu than humans. Understa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511841/ https://www.ncbi.nlm.nih.gov/pubmed/26257600 http://dx.doi.org/10.3389/fnins.2015.00255 |