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Cortical iron regulation and inflammatory response in Alzheimer's disease and APP(SWE)/PS1(ΔE9) mice: a histological perspective

Disruption of iron homeostasis and increased glial response are known to occur in brains afflicted by Alzheimer's disease (AD). While the APP/PS1 transgenic mouse model recapitulates the hallmark amyloid-beta plaque pathology of AD, it does so in a different neuronal mileu than humans. Understa...

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Detalles Bibliográficos
Autores principales: Meadowcroft, Mark D., Connor, James R., Yang, Qing X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511841/
https://www.ncbi.nlm.nih.gov/pubmed/26257600
http://dx.doi.org/10.3389/fnins.2015.00255