Robust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples

Current genomic studies are limited by the availability of fresh tissue samples. Here, we show that Illumina RNA sequencing of formalin-fixed diagnostic tumor samples produces gene expression that is strongly correlated with matched frozen tumor samples (r > 0.89). In addition, sequence variation...

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Detalles Bibliográficos
Autores principales: Graw, Stefan, Meier, Richard, Minn, Kay, Bloomer, Clark, Godwin, Andrew K., Fridley, Brooke, Vlad, Anda, Beyerlein, Peter, Chien, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511951/
https://www.ncbi.nlm.nih.gov/pubmed/26202458
http://dx.doi.org/10.1038/srep12335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511951/
https://www.ncbi.nlm.nih.gov/pubmed/26202458
http://dx.doi.org/10.1038/srep12335

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