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DNA hydroxymethylation age of human blood determined by capillary hydrophilic-interaction liquid chromatography/mass spectrometry

BACKGROUND: Aging is a complex phenomenon and characterized by a progressive decline in physiology and function of adult tissues. However, it hasn’t been well established of the correlation between aging and global DNA methylation and hydroxymethylation that regulate the growth and development of hi...

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Detalles Bibliográficos
Autores principales: Xiong, Jun, Jiang, Han-Peng, Peng, Chun-Yan, Deng, Qian-Yun, Lan, Meng-Dan, Zeng, Huan, Zheng, Fang, Feng, Yu-Qi, Yuan, Bi-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511989/
https://www.ncbi.nlm.nih.gov/pubmed/26207150
http://dx.doi.org/10.1186/s13148-015-0109-x