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IRGM1 enhances B16 melanoma cell metastasis through PI3K-Rac1 mediated epithelial mesenchymal transition

Melanoma is one of the most aggressive skin cancers and is well known for its high metastatic rate. Studies have shown that epithelial mesenchymal transition (EMT) is essential for melanoma cell metastasis. However, the molecular mechanisms underlying EMT are still not fully understood. We have show...

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Detalles Bibliográficos
Autores principales: Tian, Linlu, Li, Lixian, Xing, Wenjing, Li, Rui, Pei, Chunying, Dong, Xiao, Fu, Yanran, Gu, Changcong, Guo, Xize, Jia, Yulong, Wang, Guangyou, Wang, Jinghua, Li, Bo, Ren, Huan, Xu, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512008/
https://www.ncbi.nlm.nih.gov/pubmed/26202910
http://dx.doi.org/10.1038/srep12357