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Reduced canine BRCA2 expression levels in mammary gland tumors

BACKGROUND: Mammary tumors are the most common tumor type in intact female dogs. Recently, the breast cancer 2 early onset (BRCA2) gene was proposed to be associated with tumorigenesis in dogs. The expression level of BRCA2 is important for its DNA repair function in mammalian cells, and its express...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Yasunaga, Morimatsu, Masami, Ochiai, Kazuhiko, Ishiguro-Oonuma, Toshina, Wada, Seiichi, Orino, Koichi, Watanabe, Kiyotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512014/
https://www.ncbi.nlm.nih.gov/pubmed/26202431
http://dx.doi.org/10.1186/s12917-015-0483-9