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CHO-S Antibody Titers >1 Gram/Liter Using Flow Electroporation-Mediated Transient Gene Expression followed by Rapid Migration to High-Yield Stable Cell Lines

In recent years, researchers have turned to transient gene expression (TGE) as an alternative to CHO stable cell line generation for early-stage antibody development. Despite advances in transfection methods and culture optimization, the majority of CHO-based TGE systems produce insufficient antibod...

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Detalles Bibliográficos
Autores principales:	Steger, Krista, Brady, James, Wang, Weili, Duskin, Meg, Donato, Karen, Peshwa, Madhusudan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2015
Materias:	Technical Notes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512034/ https://www.ncbi.nlm.nih.gov/pubmed/25520372 http://dx.doi.org/10.1177/1087057114563494

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