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Treatment with 1,25(OH)(2)D(3)induced HDAC2 expression and reduced NF-κB p65 expression in a rat model of OVA-induced asthma

Recent evidence indicates that a deficiency of 1,25-dihydroxyvitamin D(3) (1,25[OH](2)D(3)) may influence asthma pathogenesis; however, its roles in regulating specific molecular transcription mechanisms remain unclear. We aimed to investigate the effect of 1,25(OH)(2)D(3) on the expression and enzy...

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Detalles Bibliográficos
Autores principales: Zhou, Y., Wang, G.F., Yang, L., Liu, F., Kang, J.Q., Wang, R.L., Gu, W., Wang, C.Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512106/
https://www.ncbi.nlm.nih.gov/pubmed/25923460
http://dx.doi.org/10.1590/1414-431X20154271