DEC2–E4BP4 Heterodimer Represses the Transcriptional Enhancer Activity of the EE Element in the Per2 Promoter

The circadian oscillation of clock gene expression in mammals is based on the interconnected transcriptional/translational feedback loops of Period (Per) and Bmal1. The Per feedback loop initiates transcription through direct binding of the BMAL1–CLOCK (NPAS2) heterodimer to the E-box of the Per2 pr...

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Detalles Bibliográficos
Autores principales: Tanoue, Shintaro, Fujimoto, Katsumi, Myung, Jihwan, Hatanaka, Fumiyuki, Kato, Yukio, Takumi, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512152/
https://www.ncbi.nlm.nih.gov/pubmed/26257703
http://dx.doi.org/10.3389/fneur.2015.00166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512152/
https://www.ncbi.nlm.nih.gov/pubmed/26257703
http://dx.doi.org/10.3389/fneur.2015.00166

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