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M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling

Endothelial nitric oxide (NO) signaling plays a physiological role in limiting obesity-associated insulin resistance and inflammation. This study was undertaken to investigate whether this NO effect involves polarization of macrophages toward an anti-inflammatory M2 phenotype. Mice with transgenic e...

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Detalles Bibliográficos
Autores principales: Lee, Woo Je, Tateya, Sanshiro, Cheng, Andrew M., Rizzo-DeLeon, Norma, Wang, Nicholas F., Handa, Priya, Wilson, Carole L., Clowes, Alexander W., Sweet, Ian R., Bomsztyk, Karol, Schwartz, Michael W., Kim, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512216/
https://www.ncbi.nlm.nih.gov/pubmed/25845662
http://dx.doi.org/10.2337/db14-1668